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40 Multimode Source for 6100 Series Single Quad LC/MS Set-Up Guide
3Methods
To create a method for alternating ESI and APCI operation
9 Click the OK button.
Figure 23 MM-ES and MM-APCI switching using Set Up MSD Signals dialog box
NOTE
In general, use the mixed mode operation (MM-ES+APCI setting with Signal 1) instead of
alternating MM-ES (Signal 1) and MM-APCI (Signal 2) mode switching. Two times as many
scans are obtained during elution of a chromatographic peak, and no delay is needed
between scans, resulting in better data. It is rarely necessary to know whether a compound
responds purely in ESI or APCI modes on a chromatographic time scale.
Ionization mode for
Signal 1 and Signal 2