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Chapter 4 Examining Chromatogram Data
4-18 Applied Biosystems
4
2. Select the method to use based upon the type of data you
are examining, then enter the associated value displayed
for the method you select:
Type of Data
Suggested
Method
Description
Higher resolution
data
Noise Filter
(NF)
(May affect
peak
resolution.)
Specify a Correlation Factor of 0 to 1.0.
Settings from 0.5 to 0.7 yield acceptable
results for most data. A setting close to 1.0
yields a higher degree of noise reduction.
If applying the Noise Filter with a certain
Correlation Factor does not yield the
necessary noise removal, return to the original
trace (see “Returning to the original trace” on
page 4-4) and apply the Noise Filter again with
a higher Correlation Factor setting. Applying
the filter more than one time with the same
Correlation Factor setting does not improve
noise removal.
Higher molecular
weight data
Gaussian
Smooth
(SM)
(May affect
peak
resolution.)
Specify a Filter Width in data points (odd
integers only). The maximum number of
smoothing points is 2001. Points less than 1
Filter Width from the edge of the spectrum are
not smoothed.